Psoriasis & Family History: Genetic Risk & Triggers

Psoriasis, a chronic skin condition, has a notable connection to family history. Individuals with a parent or other family member diagnosed with psoriasis face an increased risk of developing the condition themselves. In fact, over 20 percent of those with psoriasis report a family history of the disease.

The Genetic Component

Understanding the Role of Genes

“Genetics seems to play a large role — people with psoriasis often have a family history of psoriasis or psoriatic arthritis,” explains Shilpi Khetarpal, MD, a dermatologist at Cleveland Clinic Main Campus in Ohio. However, the relationship between genes and psoriasis isn’t straightforward. Some individuals develop psoriasis without a known genetic predisposition, while others carrying risk-associated genes never experience the condition.

Did You Know? More than 20 percent of people diagnosed with psoriasis have a family history of the condition.

Current understanding suggests psoriasis arises from a specific combination of genes interacting with environmental factors, some of which remain unidentified.

Who Can Develop Psoriasis?

Psoriasis can affect people of any race or ethnicity. While symptoms can appear at any age, research indicates two peak onset periods: between the ages of 20 and 30, and again between 50 and 60.

Expert Insight: The complex interplay between genetic predisposition and environmental triggers highlights the challenges in predicting who will develop psoriasis, even with a family history of the disease. This suggests a multifaceted approach to understanding and potentially mitigating risk.

It’s important to note that psoriasis is not contagious. It cannot be spread through casual contact, exchange of bodily fluids, or sexual contact.

Frequently Asked Questions

Is psoriasis inherited directly?

While family history increases your risk, psoriasis isn’t simply inherited. It’s a combination of genes and environmental triggers.

Can someone with no family history still get psoriasis?

Yes, some people who develop psoriasis do not have genes that increase their risk.

Are there specific ages when psoriasis is more likely to appear?

There are two peaks in onset: between age 20 and 30, and between 50 and 60.

If you have a family history of psoriasis, or are experiencing symptoms, what steps will you take to learn more about the condition?