Sexual Transmission Diseases in Puerto Rico: 2025 Data and Prevention Measures
The latest data from the Department of Health (DS) released in February of this year reveals a significant burden of sexually transmitted infections (STIs) in 2025, with 3,921 confirmed cases of genital herpes (HSV-2), 3,619 cases of chlamydia, 1,453 cases of syphilis, and 1,117 cases of gonorrhea. These figures highlight a persistent public health challenge, particularly among specific age groups and geographic regions.
Why It Matters
The data underscores stark demographic patterns. Chlamydia, gonorrhea, and syphilis predominantly affect individuals aged 20 to 34, while genital herpes shows a higher prevalence among those 45 to 54. Women accounted for the majority of chlamydia (72.1%) and genital herpes (70.7%) cases, raising concerns about targeted prevention efforts. The metropolitan region, particularly San Juan, remains the epicenter of infections, with Bayamón and Carolina also reporting high numbers.
Many STIs, including chlamydia and gonorrhea, often present without symptoms, complicating early detection. This asymptomatic nature can lead to undiagnosed spread, emphasizing the need for routine screening. The DS’s surveillance system, mandated by law, requires healthcare providers to report cases electronically, ensuring real-time tracking of trends and outbreaks.
What May Happen Next
Without enhanced prevention measures, the current trends could persist, particularly in high-risk demographics. Public health officials may prioritize expanding access to testing in the metropolitan area, where transmission rates are highest. However, the asymptomatic nature of many STIs means that underreporting remains a challenge, potentially limiting the effectiveness of interventions.

Future efforts could focus on improving education around STI symptoms and reducing stigma to encourage early diagnosis. The legal framework for reporting cases provides a foundation for monitoring, but success will depend on community engagement and resource allocation.
Frequently Asked Questions
What STIs were most commonly reported in 2025?
Genital herpes (HSV-2) had the highest number of cases at 3,921, followed by chlamydia (3,619), syphilis (1,453), and gonorrhea (1,117).
Which age groups are most affected?
Chlamydia, gonorrhea, and syphilis primarily affect individuals aged 20 to 34, while genital herpes is most prevalent among those aged 45 to 54.
Where are the highest STI rates found?
The metropolitan region, particularly San Juan, reported the highest incidence of all four STIs, followed by Bayamón and Carolina.
How might public health strategies adapt to these trends?