Brain tumor removal may improve blood sugar in diabetes patients
A recent study published in JAMA Network Open indicates that the surgical removal of a specific type of brain tumor may lead to better blood sugar management for individuals living with diabetes.
The Link Between Brain Tumors and Blood Sugar
Researchers focused on patients with olfactory groove meningiomas, which are tumors located near the base of the brain. These tumors typically affect both frontal lobes simultaneously.
The study tracked patients over a five-year period following their surgery. Researchers specifically monitored changes in body weight and hemoglobin A1c (HbA1c), a standard measurement used to track blood sugar control.
Key Findings from the Research
The research team discovered that most patients experienced improved blood sugar control after the tumor was removed. These improvements often occurred shortly after the procedure and persisted for several years.

many patients experienced weight loss following the surgery. Notably, these metabolic improvements occurred even in cases where diabetes medications remained unchanged.
Broader Implications for Metabolic Health
The results suggest that certain brain tumors may hinder the body’s ability to regulate blood sugar and metabolism. Removing these tumors may offer benefits beyond the resolution of neurological symptoms.
According to Andrew Venteicher, MD, PhD, an associate professor at the University of Minnesota Medical School and neurosurgeon with M Health Fairview, these findings raise new questions about how the brain influences metabolism throughout the body.
Potential Future Directions
Future research may explore the specific reasons why these metabolic improvements occur. Scientists may also investigate whether similar effects are present in patients with other types of brain tumors.
A possible next step is to better understand the connections between brain function, behavior and metabolism. Such insights could potentially help guide future treatment decisions for patients.
For further details, the study is available via JAMA Network Open and the University of Minnesota Medical School.
Frequently Asked Questions
What is an olfactory groove meningioma?
It is a type of brain tumor located near the base of the brain that affects both frontal lobes simultaneously.

How was blood sugar control measured in the study?
Researchers tracked long-term changes in hemoglobin A1c (HbA1c), which serves as a standard measure of blood sugar control.
Did patients have to change their medication to see results?
No, the study found that improvements in blood sugar control occurred even when diabetes medications stayed the same.
How do you think the connection between brain health and metabolic function might change the way we approach chronic illness?